Pain Relief Without Reward
An analog of naloxone targets neurons in the nucleus accumbens, providing pain relief without reward.
The Failure to Extinguish Painful Memories
What’s the difference between pain and stress? Pain causes stress, but stress does not require pain.
Pain and Addiction
The opioid addiction crisis has caused an unintended problem: chronic pain patients chronically under-prescribed.
New Gene Therapy Offers Pain Management Without Opiates
Research on mice has found a switch that regulates pain management without leading to addiction.
Cannabis Legalization Is Reducing Opioid Use
A large, geographically diverse, cross-sectional sample in multiple U.S. metropolitan areas shows cannabis legalization reduces daily opioid use.
Non-Opioid Painkiller Really Works
Two randomized controlled trials of a non-opioid painkiller show THC beats opioids in both pain relief and tolerability.